alexa Anti-Cancer Activity of Extracts of Aerial Parts of Tep
e-ISSN:2320-1215 p-ISSN: 2322-0112

Research & Reviews in Pharmacy and Pharmaceutical Sciences
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Research Article

Anti-Cancer Activity of Extracts of Aerial Parts of Tephrosia Spinosa (L.F) Pers

R Xavier Arulappa1* and K Ilango2

1Research Scholar, Karpagam University, Coimbatore – 2, Tamil Nadu, India.

2Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM University, Kattankulathur – 603203, Tamil Nadu, India.

*Corresponding Author:
R Xavier Arulappa
Research Scholar
Karpagam University
Coimbatore – 2
Tamil Nadu, India.

Received: 27/03/2013 Accepted: 14/04/2013

 

Abstract

The effect of chloroform and methanol extract of the aerial parts of Tephrosia spinosa against Dalton’s Ascitic Lymphoma(DAL) have been evaluated in Swiss albino mice .A significant increase in the life span and a decrease in the cancer cell number and tumor weight were noted in the tumor –induced mice after treatment with chloroform and methanol extract of Tephrosia spinosa (L.f) Pers.The hematological parameters were also measured in tumor-induced mice .5-Fluorouracil was used as the standard .These observations are suggestive of the protective effect of Tephrosia spinosa against DAL.

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