alexa Case Report: Angiolymphoid Hyperplasia with Eosinophili

Dermatology Case Reports
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Case Report

Case Report: Angiolymphoid Hyperplasia with Eosinophilia of the Nose

Beate Beime1 and Klaus Menges2*
1Diapharm Clinical Management GmbH, Oldenburg, Germany
2Federal Institute for Drugs and Medical Devices (BfArM), Bonn, Germany
Corresponding Author : Klaus Menges
Federal Institute for Drugs and Medical Devices
Kurt-Georg Kiesinger Allee 3, D-53175 Bonn, Germany
Tel: +49 228 207 3458
Fax: +49 228 207 3567
Received December 27, 2011; Accepted June 08, 2012; Published June 12, 2012
Citation: Beime B, Menges K (2012) Does the Requirement of Readability Testing Improve Package Leaflets? Evaluation of the 100 Most Frequently Prescribed Drugs in Germany Marketed before 2005 and First Time in 2007 or After. Pharmaceut Reg Affairs 1:102. doi: 10.4172/2167-7689.1000102
Copyright: © 2012 Beime B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


We present a case of a 62-year-old woman with a 3-year history of a red indurated plaque on the right ala of the nose, which did not respond to therapy for rosacea. A skin biopsy showed a conglomerate of thick walled vessels with a wide variation of the vessel wall diameter and a cobblestone appearance. Furthermore there were some small infiltrates with eosinophilic granulocytes. The diagnosis of ALHE was made and the patient was referred to a plastic surgeon for excision of the tumour. ALHE is a rare entity mostly found around the ears. ALHE on the nose is even more rare and could be misdiagnosed as phymatous rosacea. Misdiagnosis can lead to unnecessary treatment with antibiotics and delay of appropriate therapy.


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