alexa EVALUATION OF ANTIMICROBIAL ACTIVITY OF EUPHORBIA HIRTA AND CALOTROPIS PROCERA AGAINST MDR PATHOGENS


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Research Article

EVALUATION OF ANTIMICROBIAL ACTIVITY OF EUPHORBIA HIRTA AND CALOTROPIS PROCERA AGAINST MDR PATHOGENS

Amit Pandey1 and NehaVerma2
MRD Life Sciences Pvt Ltd, Lucknow, 226010
Received: 20th April-2013 Accepted: 29th April -2013
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Abstract

The present study is carried out by evaluation of Euphorbia hirta and Calotropisprocera against MDR cultures. In preparation of plant extract methanol, ethyl acetate, acetone and Hot water were used as a solvent. Further phytochemical analysis and MIC was performed. In Euphorbia hirta the best results were observed in methanolic extract against P.aeruginosa, S.aureus and E.coli as compare to Calotropisprocera. The leaves and stems were used as a sample part for antibiogram analysis. The least concentration was obtained 4.6 mg/ml against E.coli and 1.66 mg/ml against S.aureus in Euphorbia hirta leaves while MIC of ethylacetate extract is observed 0.75 mg/ml against E.coli, 1.66 mg/ml against S.aureus and 4.6 mg/ml against P.aeruginosa of Calotropisprocera leaves.

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