alexa Factors and Assays Identifying Babies at Risk to Develop Significant Hyperbilirubinemia
ISSN ONLINE(2319-8753)PRINT(2347-6710)

International Journal of Innovative Research in Science, Engineering and Technology
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Research Article

Factors and Assays Identifying Babies at Risk to Develop Significant Hyperbilirubinemia

Taher Abdel-Aziz1,Naglaa Azab2, Mossad Odah 3, I.M. El-deen4
  1. Lecturer,Natural Science Dept, Deanship of The Preparatory Year, Al-Jouf University , Al-Jouf, Kingdom Of Saudi Arabia- Ph-D Candidate, Biochemistry Dept, Faculty of Science, Port Said University , Port Said, Egypt
  2. Assistant Professor , Medical Biochemistry Dept, Faculty of Medicine , Benha University, Benha, Egypt
  3. Professor, Medical Biochemistry Dept, Faculty of Medicine , Benha university, Benha, Egypt
  4. Professor, Chemistry Dept, Faculty of Science , Port Said University, Port Said, Egypt
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Abstract

In this study we tested some factors associated with the prediction of hyperbilirubinemia of the newborn as cord, first day bilirubin blood levels, ABO, Rh incompatibility and use of oxytocin. This was conducted on 384 healthy term newborns, they were followed up for first 3 days of life. We analyzed bilirubin levels in cord blood and serum of the baby in first day [1]. Any baby had total serum bilirubin (TSB) more than 17mg/dL considered as having significant hyperbilirubinemia.16.1% of included newborns developed significant hyperbiliruinemia. ROC curve analysis demonstrates that the cord blood bilirubin cut off point 2.38mg/dL, and first day bilirubin cut off point 5mg/dL .There was statistically significant relation between cord bilirubin level, first day bilirubin level and subsequent hyperbilirubinemia (P <0.01).We conclude that newborns having umbilical cord blood bilirubin level >2.38 mg/dL or first day (TSB)>5 mg/ dL should be followed up in the first 3 days of life.

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