FREE RADICAL SCAVENGING AND ANTI-INFLAMMATORY ACTIVITIES OF PUNICA GRANATUM LINN.FRUIT RINDE C Baiju1*, T Jeslin2 and J Padikkala2
- Corresponding Author:
- Dr. E C Baiju
Post Graduate & Research, Department of Botany S.N.M. College, Maliankara, Ernakulam, Kerala, India
E-mail: [email protected]
Received: 12/09/2015 Accepted: 16/12/2015 Published: 21/12/2015
The methanolic extracts of Punica granatum fruit rind possess significance in vitro antioxidant and anti-inflammatory activities. The concentration needed for 50% inhibition of superoxide radical, hydroxyl radical generation, nitric oxide radical formation and lipid peroxidation were 183.3, 94.0, 53.0 and 88.5 μg ml-1 respectively. The anti-inflammatory activity of the extract was evaluated in carrageenan, BSA (Bovine Serum Albumin) and dextran induced acute and formalin induced chronic inflammatory models in balb/c mice. The extract showed significant anti-inflammatory activity in both the models comparable to control group.