alexa Investigation of an In Vitro Antimicrobial Activity of
e-ISSN: 2319-9849

Research & Reviews: Journal of Chemistry
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Investigation of an In Vitro Antimicrobial Activity of Angiopteris evecta (Forst.) Hoffm

Nilanthi SMLD, Wijayarathna C and Hettiarachchi GHCM*

Department of Chemistry, Faculty of Science, University of Colombo, Sri Lanka

*Corresponding Author:
Hettiarachchi GHCM
Department of Chemistry, Faculty of Science
University of Colombo, Sri Lanka
Tel: +94112503367
E-mail: [email protected]

Received date: 07/09/2015; Accepted date: 23/09/2015; Published date: 25/09/2015



The number of multi drug resistant starins and strains with reduced suceptibility to antibiotics are continuoesly increased. Hence searching for noval antibiotics from medicinal plants are vital. An ethno medicinal survey conducted in two different districts in Sri Lanka, especially with tribal community showed the heavy used of Angiopteris evecta (Forst.) Hoffm to cure various types of diseases. The present study was carried out to examine the in vitro antimicrobial activity of A. evecta, a pteridophyte, against the bacterial strains of Escherichia coli (ATCC 35218), Staphylococcus aureus (ATCC 25928), Klebsiella pneumonia (ATCC 13883) and Streptococcus faecalis (ATCC 9790) by agar disc diffusion assay and the fungal stains of Aspegillus niger, Fusaium oxisforum and Curvularia sp by food poison technique. The crude extracts of A. evecta were prepared in dichloromethane, acetone, methanol, chloroform and ethanol from fronds, roots and rhizomes to select the best solvent to be used in the assay. Among all the extracts tested, acetone crude extract prepared from fronds, rhizomes and roots showed the highest activity against E. coli (ATCC 35218) and S. aureus (ATCC 25928). Compared to them, K. pneumonia (ATCC 13883) and S. faecalis (ATCC 9790) showed very low level of activity. Hence, the acetone extract was used to determine the minimum inhibitory concentration (MIC) of S. aureus (ATCC 25928) and E. coli (ATCC 35218) and the MIC values were determined as 290 μg/disc and 195 μg/disc respectively. The assessment of fungal toxicity was carried in terms of percentage of mycelial growth inhibition in five different concentrations (500, 400, 300, 200, and 100 μg/ml) of ethanol, methanol, dichloromethane, and acetone, for leaves, rhizomes and roots. The ethanol and methanol extracts of leaves, roots and rhizomes showed the highest activity against the all fungal strains tested. However, A. niger showed the highest activity showing 100% inhibition of the growth at 300 μg/ml of ethanol and methanol extracts. Taking together, our results showed A. evecta is a potential source to isolate novel antimicrobial compounds.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathemat[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version