alexa Radiation Induced Salivary Gland Damage: Review on Pathogenesis and Management
e-ISSN: 2320-7949 and p-ISSN: 2322-0090

Research & Reviews: Journal of Dental Sciences
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Review Article

Radiation Induced Salivary Gland Damage: Review on Pathogenesis and Management

Dr. Sukhmani Kaur Gill1*, Dr. Ashutosh Nirola1, Dr. Anuj Paul Maini2 and Dr. Ruhi Sidhu2

1Department of Periodontology, Luxmi Bai Institute of Dental Sciences and Hospital, Patiala, Punjab, India

2Department of Oral Medicine, Luxmi Bai Institute of Dental Sciences and Hospital, Patiala, Punjab, India

Corresponding Author:
Dr. Sukhmani Kaur Gill (BDS)
Department of Oral medicine, Luxmi Bai Institute of Dental sciences and Hospital, Patiala, Punjab, India.
E-mail: [email protected]

Received date: 03/02/2016 Accepted date: 03/03/2016 Published date: 10/03/2016

 

Abstract

Salivary gland damage leading to hyposalivation and xerostomia is one of the most common complications of radiation therapy. Xerostomia and associated complications amplifies the adversities faced by a patient. Providing relief from these complications plays an important role in maintaining the overall systemic health of the patient which directly and indirectly affects the treatment outcome. This article focuses on the pathogenesis of the salivary gland damage caused by radiotherapy and the different modalities to treat and alleviate the symptoms. The various approaches include symptomatic treatment of the complications, stimulation of salivary function, and the use of radioprotector to prevent the damage along with the emerging techniques of salivary gland regeneration.

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