Screening of Preliminary Phytochemical Analysis and Antibacterial Activity of (Calotropis gigantea L. And Datura metel L.) Against Selected Pathogenic Microorganisms
Several hundreds of plant genera are used medicinally and plants are vital sources for potent and powerful drugs. Plants are exploited as medicinal source since ancient age. The traditional and folk medicinal system uses the plant products for the treatment of various infectious disease. About 75%of the Indian population relies heavily on the use of herbal drugs for the treatment of diseases. Medicinal herbs have a long history in improving human health and curing various diseases. A wide interest has been made for researchers using herbal material in identification of the active components and verification of their efficiency. Many researches are working seriously to find out substitutes for antibiotics as they cause side effects on the functioning of different parts of the body, organs and systems over the last twenty years. Ethno botanical and ubiquitous plants provide a rich resource for natural drug research and development. In the present investigation, the phytochemical and antibacterial activity of Calotropis gigantea and Datura metel. Solvent used Chloroform, Acetone and Ethanol antibacterial activity maximum in Calotropis gigantea against Staphylococcus aureus Escherichia coli, Salmonella spp, Klebsiella spp, compared to Datura metel. Synergism between plant extract and synthetic antibiotics can develop standardization of herbal medicine for treatment and prevention of infectious diseases.