alexa Search for an Herbal Medicine: Anti-Ulcer Activity of M
e-ISSN: 2321-6182 p-ISSN: 2347-2332

Research & Reviews: Journal of Pharmacognosy and Phytochemistry
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Research Article

Search for an Herbal Medicine: Anti-Ulcer Activity of Methanolic Extract of Haldina cordifolia.

Pragyandip Dash1, Anuradha Mishra2, Amit K Chaturvedi3, and Devdutt Chaturvedi1*

1Laboratory of Medicinal Chemistry, Amity Institute of Pharmacy, Amity University, Lucknow Campus, Lucknow-226028, Uttar Pradesh, India.

2Faculty of Pharmacy, Integral University, Lucknow-226026, Uttar Pradesh, India.

3Department of Chemical Sciences, GLA-University, Mathura - 281406, Uttar Pradesh, India.

*Corresponding Author:
Devdutt Chaturvedi
Laboratory of Medicinal Chemistry,
Amity Institute of Pharmacy,
Amity University, Lucknow Campus,
Lucknow-226028, Uttar Pradesh

Received: 16/08/2014 Revised: 22/09/2014 Accepted: 23/09/2014

 

Abstract

In this study, we were determining the anti-ulcer effect of Haldina cordifolia in NSAID induced rats. The methanolic extract was given orally 100mg/kg and 50 mg/kg body weight at 8 hrs interval. Diclofenac sodium was used as the inducing agent for the ulcer. The result was satisfactory as there is a marked improvement in the ulcerated part. The extract was able to decrease the acid secretion in stomach and increase the mucosal damage.

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