Cardiovascular Relating to the circulatory system, which comprises the heart and blood vessels and carries nutrients and oxygen to the tissues of the body and removes carbon dioxide and other wastes from them. Cardiovascular diseases are conditions that affect the heart and blood vessels and include arteriosclerosis, coronary artery disease, heart valve disease, arrhythmia, heart failure, hypertension, orthostatic hypotension, shock, endocarditis, diseases of the aorta and its branches, disorders of the peripheral vascular system, and congenital heart disease.
Cardiovascular science for mutations causing inherited predisposition to breast and ovarian cancer, Tuberose sclerosis, Incontinentia pigmenti, Stickler disease and Lynch syndrome are all carried out routinely by NGS. Further developments are in progress to introduce NGS to replace other existing molecular genetics and cytogenetic tests, and we aim to dramatically increase the number of genes and disorders that we can analyse using this technology in the very near future. Drug discovery is a highly complex and costly process, and in recent years, the pharmaceutical industry has shifted from traditional to genomics- and proteomics-based drug research strategies. The identification of druggable target sites, promising hits, and high quality leads are crucial steps in the early stages of drug discovery projects.
Last date updated on June, 2014