Some types of pulmonary involvement are resistant to currently available treatment regimens and thus considered as intractable conditions. These include acute/subacute interstitial pneumonia in dermatomyositis, pulmonary interstitial fibrosis in scleroderma and diffuse alveolar hemorrhage. Pulmonary hemorrhage with acute renal failure and diffuse alveolar hemorrhage in the absence of history of renal involvement or penicillamine intake rarely been reported in patients with systemic sclerosis. There are some relates of patients with systemic sclerosis and diffuse alveolar hemorrhage, some cases in pulmonary-renal syndrome. There are accumulating evidences showing the effectiveness of cyclophosphamide in patients with this intractable condition, especially those with active alveolitis.
Scleroderma Lung Disease â Other Lung Complications in Systemic Sclerosis: Maria do Socorro Teixeira Moreira Almeida
Journal of Pulmonary & Respiratory Medicine welcomes articles related to "Pulmonary hemorrhage"
Last date updated on July, 2014