Tuberculosis (TB) remains one of the worldââ¬â¢s major health problems. It is estimated that 8.6 million people developed TB, and 1.3 million died from the disease in 2012. Because of the increased drug-resistance of the causative bacterium M. tuberculosis (Mtb), about a half of the multidrug-resistant tuberculosis (MDR-TB) patients were not successfully treated globally in 2010. Thus, it is urgent to identify novel therapeutic targets for developing drugs that can treat drug-susceptible and drug-resistant TB. Since Mtb is an intracellular pathogen mainly residing in macrophages, thus elucidating the mechanisms underlying Mtb-macrophage interactions is crucial to the development of Mtb-host interfaces-targeted therapeutics.
M. tuberculosis and Macrophages: Co-existence and Co-evolution: Cui Hua Liu
Journal of Pulmonary & Respiratory Medicine welcomes articles related to "Tuberculosis"
Last date updated on September, 2024