alexa Abstract | An EGFR Pathway-Oriented Pharmacogenetic Study in Metastatic Colorectal Cancer Patients Receiving Panitumumab and Irinotecan


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Abstract

We tested the predictive value of gene polymorphisms potentially linked to the pharmacodynamics of panitumumab and irinotecan.

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Author(s): Gérard Milano, Marie-Christine Etienne-Grimaldi, Laurence Llorca, Patricia Formento, Benoist Chibaudel, Christophe Tournigand, May Mabro, Jean-Baptiste Bachet, Hélène Blons, Pierre Laurentpuig, Jean-Louis Formento, Aimery de Gramont and Thierry Andre

Keywords

Pharmacogenetics, RAS, EGFR, CCND1, EGF, UGT1A1, Panitumumab, Irinotecan, Colorectal cancer, Pharmaceutics,Alternative Medicines,Biopharmaceutics

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