alexa Abstract | Drug carriers in cancer therapy: administration, formulation and characterization

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Besides the active ingredient, matters of administration are of tremendous importance for the performance of a drug. A variety of carriers, differing in morphology and composition can be applied to enhance the efficiency of pharmaceutical active compounds. This review addresses common administration routes for cancer chemotherapy, i.e. intravenous injection, oral and transdermal application, and presents related carriers. Emphasis has been placed on vesicular systems, which are particularly useful for intravenous and oral administration. In view of considerable morphological impacts on the performance of a drug, methods for the physico-chemical characterization of carriers, covering size, encapsulation efficiency and drug release, are addressed as well.

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Author(s): Rusnah Syahila Duali Hussen and Thorsten Heidelberg

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