alexa Abstract | Generic Vs. Branded: A Comparative Dissolution Study of Some Commercially Available Levofloxacin Hemihydrate Film Coated Tablets and their Pharmacoeconomic Evaluations

Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


The main objective of the present study was to conduct a comparative study of various branded dosage forms and generic dosage form todetermine whether all the formulations were equivalent. Five different brands of marketed product of Levofloxacin Hemihydrate (250mg) (A, B, C, D, E) and one product of generic formulation (F) were purchased and were analysed. The results showed that all the branded and generic product of Levofloxacin Hemihydrate film coated tablets met the pharmacopoeial specifications. Further, all the tablets passed the hardness, thickness, length, diameter, depth, weight variation tests, disintegration time and dissolution study as per pharmacopoeia. Disintegration time for generic product was found to be 15.1 ± 1.153 minutes which was higher than all the branded products. The dissolution study data of all the formulations passed the test as per the pharmacopoeia. Further, it was observed from the dissolution data that of the five branded products; three of these released the drug in 15 minutes and the remaining two in 20 minutes while the generic product released the drug in 30 minutes. Hence it may be conclude that all the branded products and the generic form of Levofloxacin Hemihydrate film coated tablets (250mg) were found to be equal, hence generic product should be prescribed by health care professionals as the cost of generic product is comparatively less to an extent of 30-50 % of the branded products which may reduce the cost of medication to the patients.

To read the full article Peer-reviewed Article PDF image

Author(s): Mona Patel, Abhay Dharmasi


Levofloxacin hemihydrate, generic product, branded product, dissolution, Transmission of Diseases from Mother to Child

Recommended Journals

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version