alexa Abstract | Interaction of Hyperoside and β-sitosterol with Alanine Transaminase using Molecular Docking


Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Alanine transaminase (ALT) is a transaminase enzyme found in serum and in various body tissues. Elevated levels of ALT suggest the existence of disease such as liver damage, diabetes etc. Hyperoside, β-sitosterol was taken as ligand for molecular docking with Type 2 diabetic targets. Alanine transaminase enzyme whose crystallographic structures are available on the PDB database as 3IHJ was used for the docking analysis using the Schrodinger tool. The docking studies of the enzyme Alanine transaminase with two ligand hyperoside and β-sitosterol reveals that these are the good molecules which docks well with targets related to diabetes mellitus. Metformin is used as a standard drug for docking with Alanine transaminase. Hence hyperoside and β-sitosterol can be considered for developing into antidiabetic drug.

To read the full article Peer-reviewed Article PDF image

Author(s): M. Uma Makheswari, D. Sudarsanam

Recommended Journals

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords