alexa Abstract | Synthesis and Anticonvulsant Activity of Indolo-Imidazolone Hybrid Molecules
JOMC

Research & Reviews: Journal of Medicinal & Organic Chemistry
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

A series of hybrid molecules comprising of indole and imidazolone moieties (4a-g and 5a,b) was synthesized with a view to obtain promising anticonvulsant molecules. Anticonvulsant activity of the title compounds was determined in MES and scPTZ animal models. Neurotoxicity studies were also performed to estimate the undesired effects of the compounds. Majority of the compounds showed appreciable activity against both the animal models whereas compounds 5a and 5b showed good activity and could be considered as leads for further investigations

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Asif Husain, Aftab Ahmad, Fahad Al-Abbasi, Shah Alam Khan

Keywords

Indole, imidizalolone, Mice, Anticonvulsants, Indole, imidizalolone, Mice, Anticonvulsants.

Share This Page

Additional Info

Loading
Loading Please wait..
 
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords