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ISSN: 2329-9053

Journal of Molecular Pharmaceutics & Organic Process Research
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Eburnation is described as a specific type of bone sclerosis consisting of a marbled appearance of weight-bearing joints with complete cartilaginous erosion, leaving polished, sclerotic bone as the new articular surface bone, it is commonly seen in patients with osteoarthritis or non-union of fractures.Cross-section of the articulation reveals a narrowed joint space, osteosclerosis and cystic changes overlying the affected bone, which is surrounded by bony and cartilaginous overgrowths (osteophytes/exostoses).

Eburnation describes a degenerative process of bone commonly found in patients with osteoarthritis or non-union of fractures. It is an ivory-like reaction of bone occurring at the site of cartilage erosion. Osteoarthritis is a degenerative disease of the joints characterized largely by central loss of cartilage and compensatory peripheral bone formation (osteophytes). Over time, as the cartilage wears away, bare, subchondral bone is revealed. Eburnation describes the bony sclerosis which occurs at the areas of cartilage loss.

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