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Pneumonia is an inflammatory infection in the lung that affects the air sac known as alveoli that are filled with pus or fluid making it difficult to breathe. Pneumonia is caused by numerous factors, such as environmental contaminants and autoimmune diseases, as well as infection. Pneumonia is usually caused by infection with viruses, bacteria or fungi and less commonly by other microorganisms. Signs and symptoms of pneumonia include fever, sweating, shortness of breath and chest pain.