The pathogenicity of Staphylococcus aureus has long been established. It is by far the most important and virulent pathogen among the staphylococci and can cause disease in otherwise healthy individuals. Apart from skin and soft tissue infections (SSTIs), Staphylococcus aereus can cause such other serious infections as bacteremia or sepsis, staphylococcal pneumonia, bacterial endocarditis, osteomyelitis and toxic shock syndrome. Staphylococcal sepsis is a leading cause of shock and circulatory collapse and if untreated Staphylococcus aureus sepsis carries a high mortality rate (11-43%) especially in cases of severe and extensive burns. S. aureus has also been reported as a causative factor, although on a small scale, for chorioamnionitis and neonatal sepsis in pregnancy. S. aureus is an important cause of both healthcare- and community - associated infections having acquired resistance to most antibiotics currently in use thus complicating the treatment of S. aureus infections.
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Last date updated on June, 2014