Stem cell therapy for cardiac disease is an exciting but highly controversial research area. Strategies such as cell transplantation and reprogramming have demonstrated both intriguing and sobering results. Yet as clinical trials proceed, our incomplete understanding of stem cell behavior is made evident by numerous unresolved matters, such as the mechanisms of cardiomyocyte turnover or the optimal therapeutic strategies to achieve clinical efficacy. In this Perspective, we consider how cardiac stem cell biology has led us into clinical trials, and we suggest that achieving true cardiac regeneration in patients may ultimately require resolution of critical controversies in experimental cardiac regeneration. Scientific journal is a periodical publication intended to further progress of science, usually by reporting novel research. There are thousands of scientific journals in publication, and many more have been published at various points in the past. Most journals are highly specialized, although some of the oldest journals publish articles and scientific papers across a wide range of scientific fields. Scientific journals contain articles that are peer reviewed, to ensure that articles meet the journal's standards of quality, and scientific validity. The publication of the results of research is an essential part of the scientific method. If they are describing experiments or calculations, they must supply enough details that an independent researcher could repeat the experiment or calculation to verify the results.
Last date updated on July, 2014