Dehydroepiandrosterone (DHEA) is an adrenal steroid circulating abundantly as a sulfate conjugated form DHEA-S. DHEA-S reaches a maximal plasma level between 15 and 25 years old and the following decline in DHEA-S has been related to aging-associated diseases development. DHEA is a potent uncompetitive inhibitor of the first enzyme in the pentose phosphate pathway (PPP), the mammalian glucose-6-phosphate dehydrogenase (G6PDH). Studies performed on Sardinian males bearing a Mediterranean variant of G6PDH deficiency, support the hypothesis that reduced G6PDH activity has a beneficial effect on age-related disease development.
Journal of Steroids & Hormonal Science publish the articles in the topics of dehydroepiandrosterone. The journal is having highly qualified professors and associate professors in hormones or steroid hormones as editoial board members and review board members. The papers published by the journal are online and these papers are peer reviewed by the expert editorial board and review board. Hence, the quality of the papers being published is being maintained. Unofficial impact factor of Journal of streoids & Hormonal Science is 3.125.
Last date updated on July, 2014