Steroid hormones are synthesized in the adrenal gland, placenta, and gonads. The major building block in steroidogenesis is cholestrol, and except placenta all other all steroid-producing tissues have the capacity of synthesizing cholesterol from acetate a 2-carbon precursor. In Steroid hormone production, at least 17 enzymes are involved, primarily occurs in the abundant smooth endoplasmic reticulum found in steroidogenic cells.
Steroid Hormones are mainly metabolized in the liver and to a lesser extent in the kidney and intestinal mucosa. similarly, administration of few pharmacologic steroid hormones may be restricted in those with active liver disease. Based on the number of carbon atoms sex steroids are divided into three groups. Every carbon in this structure is assigned a number identifier, and each ring is assigned a letter. The journal of Steroids & Hormonal Science publishes the papers on Steroid hormone metabolism under a special issue entitled "Steroid hormone metabolism" which is being edited by Dr. Carin Wittnich, University of Toronto, Canada . The journal is open access and hence the content can be accessed freely by the readers and the papers which will be published in the journal are subjected to peer review process and the findings are assesed by experts for the quality.
Last date updated on June, 2014