Toxic kinetics is defined as the passage through the body of a toxic agent or its metabolites ,Toxicokinetics is the study of systemic exposure during toxicological experiments. The objective is to quantify the systemic exposure and potentially relate that to toxicology findings. The comparison of toxicology exposure parameters to therapeutically effective exposure parameters gives rise to the idea of a therapeutic window, or the space between efficacy and toxicity. This is depicted in a theoretical example below.
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Last date updated on July, 2014