There are several early-stage innovative technologies in development that are aimed to meet the cell supply problem faced by regenerative medicine. All are based on the unique biological properties of stem cells.These technologies employ unipotent and multipotent tissue-specific distributed stem cells.Past advances in technologies for biopharmaceutical manufacturing included effective methods for large-scale production of mammalian cell lines used to produce therapeutic biomolecules and vaccines. However, in these conventional processes, the cells are a waste product that is discarded. Bridging the technological gap between early-stage innovations like SACK, for producing normal human cells on-demand, and the technological need of regenerative medicine for routine supply of normal human cells will require a new type of technological development that produces normal human cells â stem and/or mature â as the desired product. (James L Sherley, Accelerating Progress in Regenerative Medicine by Advancing Distributed Stem Cell-based Normal Human Cell Biomanufacturing)
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Last date updated on November, 2020