Tuberculosis (TB) remains one of the worldââ¬â¢s major health problems. It is estimated that 8.6 million people developed TB, and 1.3 million died from the disease in 2012. Because of the increased drug-resistance of the causative bacterium M. tuberculosis (Mtb), about a half of the multidrug-resistant tuberculosis (MDR-TB) patients were not successfully treated globally in 2010. Thus, it is urgent to identify novel therapeutic targets for developing drugs that can treat drug-susceptible and drug-resistant TB. Since Mtb is an intracellular pathogen mainly residing in macrophages, thus elucidating the mechanisms underlying Mtb-macrophage interactions is crucial to the development of Mtb-host interfaces-targeted therapeutics.
M. tuberculosis and Macrophages: Co-existence and Co-evolution-Cui Hua Liu
OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals with the dramatic effort of editorial board members. Journal of Tropical Diseases & Public Heath publishes original research articles, novel, and scientifically sound findings dealing with tropical diseases related to human health.
Last date updated on September, 2024
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