Journal of Antivirals is one among the best top peer-reviewed journals in the world. The journal covers the whole field of antivirals and Virosomes. The study mainly focuses on antiviral drugs, Antiviral drugs are 1 class of antimicrobials which also include antifungal, antimicrobial, and antiparasitic . The antiviral drugs are harmless to the host and therefore can be used to treat different viral infections. Antivirals can also be found in essential oils of some herbs, with the help of ayurveda such as eucalyptus oil and its constituents.
A virosome is a drug or vaccine delivery mechanism consisting of unilamellar phospholipid membrane it may be mono- or bi-layered. Vesicle incorporating virus derived proteins to allow the virosomes to fuse with target cells. Virosomes are not able to replicate but are pure fusion-active vesicles.
The development of safe and effective models for the delivery of any prophylactic or therapeutic agent remains an uphill task for pharmaceutical formulation developers. Drug molecules, nucleic acids, carbohydrates, proteins and a variety of other biological and chemical entities are used for attaining pharmacological benefits. However, the major challenge remains in the delivery of these agents to the specific site of action in a time-efficient manner. Among the many drug delivery systems developed, the nano scale technology of virosomes tends to present an established system of delivering the therapeutic agents to the site of pharmacological action. Virosomes are lipid bilayer, unilamellar structures that present viral protein on their surface. They are safe, biocompatible and biodegradable structures that can achieve ideal pharmacological profile once administered into the body. Tissue targeting, immune activation and potentiation are the chief advantages that make them efficient prophylactic and therapeutic agents. The review presents the biopharmaceutical applications of virosomes and the immunological and pharmaceutical considerations that make them efficient agents for targeting spatiotemporal parameters in the body..
Last date updated on June, 2014