|Preterm birth is defined as delivery before 37 weeks of gestation. It is the leading cause of neonatal death and infant mortality, often as a result of respiratory distress syndrome due to immature lung development. Babies who survive are also at high risk of neurological disability and can experience further breathing, feeding, digestive, visual, and hearing problems. Observational studies have found that a prior history of preterm birth significantly
Births that follow spontaneous preterm labor (PTL) and preterm premature rupture of membranes (pPROM) are together designated as spontaneous preterm births. Spontaneous preterm births account for ~70% of all premature deliveries, where the remaining 30% are indicated as a result of maternal or fetal infection. Of those births classified as spontaneous preterm births, 64% are the result of preterm labor (PTL) and 36% are are the result of preterm premature rupture of membranes (pPROM).
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