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Resolution of Inflammation and the Plasminogen/Plasmin System Interaction
Inflammation is a complex biological response that plays a critical role in the body's defense against harmful stimuli, such as pathogens, tissue injury, and other insults. While inflammation is essential for maintaining tissue homeostasis, an excessive or prolonged inflammatory response can lead to tissue damage and chronic dis.. Read More
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This comprehensive review, authored by the International Association for the Study of Lung Cancer (IASLC) Early Detection and Screening Committee, critically examines the intricate relationship between air pollution and lung cancer. With increasing global concerns about air quality and its impact on public health, this review sy.. Read More
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Understanding How Polyunsaturated Fatty Acids and Cancer are Related from Genes to Tumours
This article delves into the intricate interplay between polyunsaturated fatty acids (PUFAs) and cancer, spanning from genetic variations to the complexities of tumour development. PUFAs, essential components of the human diet, have been implicated in cancer biology, with recent research highlighting the role of genetics in modu.. Read More
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Unraveling the Genetic Link: Polyunsaturated Fatty Acids and Cancer Risk
This article delves into the intricate relationship between polyunsaturated fatty acids (PUFAs) and cancer risk, with a focus on the genetic factors that underlie this association. PUFAs, essential components of the human diet, have garnered attention for their potential roles in cancer prevention and treatment. Recent advanceme.. Read More
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Regulation of Ferroptosis: Uncovering Mitochondria-Related Signalling Pathways in Breast Cancer
Breast cancer, a multifaceted and prevalent disease, remains a formidable challenge in oncology. Recent advances have highlighted the role of mitochondria-related signaling pathways in shaping breast cancer progression and response to treatment. Intriguingly, these pathways intersect with the regulation of ferroptosis, a unique .. Read More
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Basal-like breast cancer (BLBC) poses significant challenges due to its aggressive behavior and limited treatment options. Recent investigations have uncovered a promising avenue for addressing BLBC through the modulation of the FOXO1-KLF5 transcriptional axis by DNA damage chemotherapeutic drugs. In this study, BLBC cell lines .. Read More
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Squamous Cell Oral Cancer with Cervical Metastases and Cyclin D1 Expression
The most important prognostic factor for oral carcinomas is cervical metastasis. Cervical metastasis is influenced by clinical and histological variables, but recent years have seen a significant increase in the study of molecular factors. Aim: This study's objective is to examine the Cyclin D1's potential role as a risk factor.. Read More
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Background: In patients with advanced-stage lung cancer and IIP, the clinical questions regarding whether chemotherapy as the initial treatment improves overall survival (OS) and whether it increases the occurrence risk of acute exacerbation of idiopathic interstitial pneumonia (IIP) remain unanswered. Given that chemotherapy-re.. Read More
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Secondary Lymphedema Prevalence in Head and Neck Cancer Patients
Context: Since medical procedure, radiation, or potentially chemotherapy disturbs lymphatic designs, harm delicate tissue prompting scar tissue arrangement and fibrosis, and further influence lymphatic capability, patients with head and neck disease might be at high gamble for creating auxiliary lymphedema. However, there are no.. Read More
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Elderly Stage III Colon Cancer Patients in the Netherlands: Treatment and Side Effects
Background: In elderly colon cancer patients, we investigated which patient factors were associated with treatment tolerance and outcome. Design: Populace based information from five districts remembered for the Netherlands Malignant growth Library were utilized. Patients with resected stage III colon disease matured ≥75 .. Read More
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As the pattern of disease shifts from infectious diseases to non-communicable diseases like breast cancer, the most common cancer among women in middle resource countries (MRCs), cancer control programs are becoming a priority.The Center Asset Situations Working Gathering of the BHGI 2010 Worldwide Highest point met to recognize.. Read More
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Impact on Breast Cancer Mortality of Breast Cancer Screening in Case- Control Studies
Background: Different levels of breast cancer mortality reduction have been shown in recent case-control studies on the efficacy of population-based breast cancer screening. We looked into how the case-control research design's elements, such as the definition of cases and exposure to screening, affected these discrepancies. Ma.. Read More
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Expression of the Cancer-Testis Antigen in Triple-Negative Breast Cancer
Background: Disease testis (CT) antigens, regularly communicated in human germline cells yet not in physical tissues, may become unusually reexpressed in various malignant growth types. The expression of CT antigens in breast cancer was the focus of this study. Patients and methods: Immunohistochemistry was used to examine the .. Read More
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Background and purposes: Stereotactic Body Radiotherapy (SBRT) is the main treatment modality for earlystage NSCLC patients who cannot undergo the operation because of its excellent local control as well as Overall Survival (OS) rates. However, in patients with centrally located tumors, the radiation induced side effects to surr.. Read More
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Enhanced Temozolomide Resistance in Glioblastoma by the Novel Cancer Stem Cell Marker MVP
In this study, we discovered that CSEs from HTPs induced CSC marker expression and proliferation in the lung. In addition, the HTPs' CSEs induced the expression of EMT markers and inflammatory cytokines, indicating that HTP aerosols may contain harmful chemicals that could influence lung cancer development. These information rec.. Read More
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Several types of cancer, including lung cancer, have been linked to an increased risk of smoking by epidemiological studies. Cancer stem cells (CSCs), a minor cell population in tumors that contribute to drug resistance and recurrence, are the source of lung cancer. Aerosols made from heated tobacco products (HTPs) contain nicot.. Read More
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Disease undifferentiated cells (CSCs) are a subpopulation that can drive repeat and metastasis. In this way, treatments focusing on CSCs are required. The precise molecular mechanism by which non-CSCs regulate CSC proliferation and differentiation in the tumor microenvironment is largely unknown, despite previous findings sugges.. Read More
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A Comparison of the Ability of Three Different Cancer Stem Cell Cultures to Spread
One of the main causes of cancer deaths is metastasis. In any case, the systems of disease cells gaining forcefulness and metastatic potential are still being scrutinized. Despite the fact that cancer stem cells (CSCs) have been proposed as the cells that start tumors and are responsible for cancer metastasis, no sufficiently pr.. Read More
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Background: The study aims to estimate the incidence of pancreatic cancer in people with new-onset type 2 diabetes (T2DM) and examine the connection between pancreatic cancer risk, age at diagnosis, and duration of diabetes. Methods: Mendelian randomization (MR) in the east-Asian population and this longitudinal cohort study wi.. Read More
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The synthesis, characterization, and biological properties of Iron Oxide with Lanthanum and Yttrium oxide nanoparticles were discussed. The samples were prepared using the microwave-accelerated technique. The products were characterized using X-ray diffraction (XRD) and Vibrating Sample Magnetometer (VSM), and also subjected to .. Read More
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