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A Review on Toxicity of Carbon Monoxide on Human
Carbon monoxide toxicity becomes a momentous health issue in USA and many other countries. This toxicity causes severe morbidity and mortality and its symptoms resemble with other illness. Source of CO include, second hand smoke, fumes from heating systems burning fuels, exhaust fumes from motor vehicles. One of the most frequen.. Read More
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Arsenic Toxicity, Vitamin C and PON1
Arsenic exposure affects millions of people worldwide. It increases the formation of Reactive oxygen species (ROS), oxidative stress and decrease antioxidant cell defense. Because of the role of ROS in the development of atherosclerosis disease, use of using antioxidants such as vitamin C (increasing PON1 activity as an antioxid.. Read More
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Novel Benzo[d]thiazole with Dimethylpyrazol Derivatives: Design, Synthesis and Biological Evaluation
A series of new benzothiazole derivatives containing dimethylpyrazole were synthesized and evaluated for their anticonvulsant activity, neurotoxicity and cytotoxicity by using the maximal electroshock (MES), rotarod neurotoxicity (TOX) and MTT colorimetric assay. Among the compounds studied, four compounds (6a, 6b, 6g and 6m) sh.. Read More
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The study evaluate the acute toxicity of aqueous extract of Adenium obesum stem bark to determine the median lethal concentration (LC50) in exposed Clarias gariepinus under laboratory conditions using static non-renewal bioassays over a 96-h exposure with continuous aeration. The fish (N=180, mean weight and length 21.48 ± .. Read More
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Chromium III in Gezira Tannery Corporation Wastewater (Wad Medani, Sudan)
This study was initiated to investigate the level of chromium III in Gezira Tannery Wastewater and compared with the permissible limit stander for chromium III. Samples of Gezira Tannery Corporation (GTC) wastewater (WW) were collected from both the mouth and the tail of the drainage stream. These samples were analyzed to determ.. Read More
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Determination of the Activity of ALT and AST Enzymes of Blood in the Sheep Infected with Helminthes
This study determined liver enzymes activity (ALT) and (AST) in blood of sheep and faecal egg counts in the dry (August) and wet (November) seasons in Absheron region of Azerbaijan. Total 84 sheep were included for this study. Research results showed that faecal egg counts were significantly higher in the wet compared with the d.. Read More
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Safety Evaluation of Rayner's Flavor Banana® in Swiss Albino Mice
Safety evaluation of Rayner’s Flavor was carried out in Swiss albino mice and 52 mice were used for the evaluation. Forty out of 52 mice were used for determination of median lethal dose (LD50) using modified arithmetical method of Reed and Muench. The LD50 was determined at dose rate of 0.35 ml. Another 12 mice were divid.. Read More
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The microbiological and physiological analysis of crude oil contaminated soil amended with animal wastes (Chicken droppings and Cow dung) were investigated using standard cultural techniques and different concentrations of nutrients amendments (10%, 30% and 50%). The present study was aimed to isolate and identify microorganisms.. Read More
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Neurologic and Pregnancy Effects of Carbon Monoxide Exposure
Carbon monoxide exposure remains a public health concern worldwide. Despite the burden that carbon monoxide exerts, significant controversy exists regarding optimal treatment of exposed persons. Particular controversy around neurologic effects of carbon monoxide exposure, how best to evaluate for neurocognitive dysfunction, and .. Read More
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The discovery of antibiotics has contributed significantly to improving the life expectancy of the global population. Nowadays, the emergence of multi resistant strains of bacteria worldwide is a major concern as it dramatically reduces the choice of effective antibiotics for prevention and treatment of a very common infection i.. Read More
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Jellyfish Envenomation with Skin and Cardiovascular Manifestations and Treatments
Jellyfish are smooth-formed animals in the phylum cnidaria, living in around coastal water zones worldwide. Interacting with jellyfish tentacles, even the beached and dying jellyfish, can prompt millions of nematocysts to perforate the skin and infuse the venom through the inverted long spiny tubules, thereby causing toxic manif.. Read More
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High Throughput Detection Methods for Multiplex Mycotoxins
Mycotoxins are toxic low-molecular-weight compounds which produced by the metabolism of certain fungi species. Due to their toxicity, chemistry stability, diversity and co-occurrence in agriculture products, it is urgently needed to develop the rapid, simple and effective detection technique methods to monitor and prevent mycoto.. Read More
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Research on Nanotoxicity of an Iron Oxide Nanoparticles and Potential Application
The iron oxide nanoparticles (FeNPs) are widely used in biomedicine for good biocompatibility. To promote its safe application, any potential nanotoxicity should be thoroughly and carefully investigated. This paper systematically summarizes our lab’s research on the nanotoxicity of iron oxide nanoparticles coated with dime.. Read More
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The Drug iatrogenesis corresponds to the pathology or any clinical manifestation undesirable for the patient induced by the administration of one or more medicines. Several studies have estimated that adverse drug reactions account for between 0.5% and 2% of outpatient consultations and are involved in 4% to 10% of hospital admi.. Read More
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Development of International Standard on Nano Aerosol Generation for Inhalation Toxicology Study
Development ISO TR 19601 : Aerosol generation for NOAA (nano-objects and their aggregates and agglomerates) air exposure studies is completed recently. The technical report (TR) reviews methods for generating aerosols of NOAA for in vivo and in vitro inhalation studies. The goals of this technical report is to aid in selecting a.. Read More
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Fumonisins in Foods from Cordoba (Argentina), Presence: Mini Review
This review emphasizes, specifically, the determination of fumonisins in different food substrates, made in different commercial centers of Córdoba, Argentina. The importance of reviewing this research is related to public health, since food is part of human development and this must be safe. These contaminations, which we .. Read More
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Background: Arenaviruses are important pathogens that can cause hemorrhagic fever or meningoencephalitis. There is not an effective treatment targeting arenaviruses, which necessitates a search for therapies against this virus family, as well as others. Silver nanoparticles (Ag-NPs) have been shown to have effective antiviral ac.. Read More
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Introduction: Organophosphorus poisoning (OPP) is an important health problem in many parts of the world particularly in developing countries. However, the treatment did not change since many years, despite the increasing complications and case fatalities of the exposure. From the clinical experience, some pharmacologic agents h.. Read More
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Lactational Exposure to Pesticides: A Review
The aim of this study is to review the reports of pesticides have been detected in human breast milk in worldwide. Contamination levels of pesticides such as organochlorine pesticides (OCPs), organophosphorus pesticides (OPPs), carbamates and pyrethroids in human breast milk were found to be varied in different countries. The ch.. Read More
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Methanol Poisoning with Fatality- Case Series in Dhaka Medical College Hospital in Bangladesh
Background: Adulterated methanol is highly toxic and leads to severe metabolic acidosis and blindness and mortality is very high if not treated with specific antidote. The time of ingestion and severity of illness is very short and comprehensive quick assessment and care is crucial for survival of patient. The selective antidote.. Read More
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