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Updates in Medication for Sturge-Weber Syndrome: A Mini Review
Sturge-Weber Syndrome is a rare neurovascular disease associated with glaucoma, a port wine birthmark and most commonly, leptomeningeal vascular malformations accompanied by medically refractory epilepsy. Due to the poorer prognosis associated with extensive brain involvement and early onset of seizures, aggressive and early dia.. Read More
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Surfactant Metabolism Dysfunction Type 3 (SMDP3)
Surfactant (surface-active-agent) is a compound of phospholipids and proteins which are synthesized and secreted into the alveolus by type II epithelial cells, where it functions to decrease surface tension, maintaining alveolar expansion, to facilitate pulmonary compliance. Surfactant Proteins (SP) A, B, C, D represent around .. Read More
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The objective of this meta-analysis was to determine the association between Employment status of mothers and acute malnutrition among under five children in Ethiopia.Using data from 11 studies in Ethiopia we performed a meta- analysis with a specific focus on acute malnutrition among under five children. We applied a random ef.. Read More
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Challenges with Peripherally Inserted Central Catheter Migration in Neonates
The use of peripherally inserted central catheter in neonatal intensive care unit is a common practice, but it is associated with various complications. Catheter migration is the most common complication in neonates. The incidence of PICC migration in neonates ranges from 8% to 33%. The majority of the PICC migration is seen in .. Read More
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A Giant Omphalocele (GO) with marked viscero-abdominal disproportion is associated with surgical difficulty and higher morbidity and mortality rates. Despite various treatment strategies, no consensus exists on optimal GO management. We report our experience of a neonate with a GO that overcame the major therapeutic challenges (.. Read More
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Background and objective: This study aims to detect how hyperbilirubinemia affects cerebral structures by imagery (MRI and DWI) to prevent irreversible future brain damage. It will equally help us examine the relationship between imaging and neurodevelopment. Research design and methods: In a retrospective, controlled study, 50.. Read More
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Newborn Screening for Cystic Fibrosis in Genetically Heterogeneous Populations
Cystic fibrosis is the most frequent autosomal recessive disease in Caucasians. Survival improves with the implementation of newborn screening programs that enable early detection and rapid initiation of treatment to reduce the effects of the disease. Not all available algorithms for newborn screening are suitable for all popula.. Read More
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Rare Homicidal Organophosphorus Poisoning in a Neonatal Twins
Organophosphate (OP) compounds widespread use throughout the world, mainly in agriculture, may cause serious life-threatening conditions. We report the case of neonatal twins presented with poor feeding, lethargy, jerky respiration and excessive frothy secretions, pinpoint pupils and bradycardia. Father disgruntled over his wife.. Read More
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Consideration of Doctors' Identity and Socialization Mechanisms through Variation Theory
Doctors’ socialization emerges from the interaction of professional identity formation (PIF) and context. We previously reported that medical students considered their career and junior residents adapted as physicians in forming their PIF. Following this, four patterns of doctors’ socialization emerged, all in the in.. Read More
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Congenital Uterine Anomalies, Preterm Birth and Cervical Cerclage: A Mini-Review
It is unknown to what degree the congenital uterine anomalies contribute to preterm birth. Even less data exists regarding what percent of these are due to cervical incompetence and if cervical cerclage improves newborn outcomes. This mini-review seeks to review of the risk of preterm birth in women with congenital uterine anoma.. Read More
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Prognostic Value of Liver Histology at the Time of Kasai Procedure in Children with Biliary Atresia
Objectives: Biliary atresia is a chronic cholestatic disease resulting from irreversible extrahepatic bile duct occlusions, which leads to liver transplantation in childhood. Solid prognostic values are lacking. Methods: We investigated the prognostic validity of the PELD score and other laboratory parameters that concern the t.. Read More
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Oral Implications of Parafunctional Habits in Children: A Mini-Review
Habits are unconsciously performed repetitive actions. Functional habits actions like nasal breathing, chewing, and swallowing is essential for the growth and development of a child. Para functional habits on the other hand, result from unnecessary actions and have a detrimental effect on the growth and development of a child. T.. Read More
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Cesarean Section Trend and its Correlates in Nepal: A Mini-Review
CCesarean Section (CS) is the important indicator of emergency obstetric care performed to save maternal and fetal lives by preventing complications during labor. This study aimed at identifying the trend of CS over two decades in Nepal and also find out its correlates. National demographic and health survey (NDHS) data from the.. Read More
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Posterior reversible encephalopathy syndrome (PRES) is a rare cause of acute encephalopathy but can be observed in children under chemotherapy. We herein report a case of PRES in a 13-year-old boy with an acute lymphoblastic leukemia following treatment with intrathecal and intravenous chemotherapy. On Magnetic Resonance Imaging.. Read More
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Clinical Evaluation of Neonatal Malaria in a Sub-urban Healthcare Facility in South-East Nigeria
Background: Malaria is a major killer in children under-5 years of age. Its incidence in neonates is commonly mis-diagnosed as sepsis and thus under-reported. Sometimes, a high index of suspicion for malaria in the neonate is necessary to make a diagnosis. Documentation of the clinical features of malaria in neonates and predict.. Read More
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Introduction: Vitamin D is classically involved in the regulation of calcium and phosphate homeostasis. It is increasingly being recognized to have a multitude of effects on various cell systems and signaling pathways. Vitamin D level of the mother during pregnancy is also assuming great importance as it is expected to have the .. Read More
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Pediatric Migraine Treatment: An Updated Review
Introduction: Migraine is the most important cause of pediatric consultations due to headaches, because of significant distress and disability for child and their family. For this reason, a correct and timely treatment is very important. Objectives and methodology: This article reviews the current knowledge about migraine treat.. Read More
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Background: A 41-year systematic literature review of early infancy osteomyelitis was performed. Observations were made regarding variables related to the diagnosis and treatment of the disease. We asked: 1) since magnetic resonance imaging (MRI) technology was introduced into diagnostic protocol in 1998, has there been an impro.. Read More
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The aim of the study was to compare the executive function (EF) between soccer trained (ST) and untrained (UT) 6-11 year old children. In addition, the relationship between EF and aerobic fitness was evaluated. In all, 18 ST children and 12 UT children participated in this study. EF was evaluated using the ADAM4 battery. Pulmona.. Read More
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Objectives: The primary objective of the study was to minimize the waste because of stocked supplies at the bedside cabinet in NICU. The aim was to find alternative options to stock, and to educate care providers about the increase in cost of the patient care arising because of the waste associated with inadequate inventory mana.. Read More
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