Generation of neurons from neural stem cells and progenitor cells is known as neurogenesis. Whereas adult neurogenesis deals with generation of neurons after fetal and early postnatal development has ceased. Adult neurogenesis only appears to occur in the hippocampus and olfactory bulb. To replace olfactory receptor neurons constantly high level of adult neurgenesis is carried out in olfactory epithelium. Most of the vertebrates and invertebrates have the capacity of neural regeneration with the process of adult neurogenesis, example for this process is regeneration of tail in salamanders. Even it is widespread mechanism to all classes of vertebrates but limited to some classes of vertebrates such as certain birds, fish and reptiles. Experiments are going on from many years to understand neuronal maturation, developmental process and regulation of adult neurogenesis, including proliferation, targeting, fate specification, and synaptic integration of the newborn neurons. For structural plasticity in the mature CNS environment adult neurogenesis is the striking example.
Last date updated on June, 2014