Airway inflammation is a state of disturbance in the airways where the immune system responds to an apparent threat and causes swelling, itching, redness, and different side effects. Airway inflammation can occur in response to exposure to particulates like dust, toxins, allergens, and different substances. Features of the disease are reversible airflow obstruction, extensive leukocyte infiltration, mucus overproduction, airway hyperresponsiveness and inflammation leading to tissue damage and remodeling. Exhaled nitric oxide is an effective biomarker for airways inflammation. Airways are highly affected in asthma, COPD, allergic rhinitis and other respiratory diseases. The airways are narrowed which is associated with airway hyperresponsiveness and variable airflow obstruction. Multiple cell types such as T helper 2 cells, regulatory T cells, eosinophils, dendritic cells, mast cells, and parenchymal cells of the lung are involved in the pathogenesis. Chronic inflammation can possibly cause irreversible changes to the airways in the lungs.
Scientific journal is a periodical publication intended to further progress of science, usually by reporting novel research. There are thousands of scientific journals in publication, and many more have been published at various points in the past. Scientific journals contain articles that are peer reviewed, to ensure that articles meet the journal's standards of quality, and scientific validity. The publication of the results of research is an essential part of the scientific method. If they are describing experiments or calculations, they must supply enough details that an independent researcher could repeat the experiment or calculation to verify the results. Each such journal article becomes part of the permanent scientific record.
Last date updated on July, 2014