Allergen immunotherapy, also called desensitization aims at patients suffering from allergies. It is a long-term treatment which decreases allergic symptoms by increasing tolerance to the specific allergen and involves the repeated administration of allergenic extracts to the patients either subcutaneously or sublingually for the treatment of allergic respiratory diseases. Allergen immunotherapy improves the existing symptoms of allergic rhinitis, conjunctivitis, asthma or stinging insect allergy. Allergen immunotherapy is the cost-effective adjunctive treatment in modifying the existing disease state. This immunotherapy is associated with a shift from Th2 to Th1 immune responses, and the production of T regulatory cells that reduce the immune response to relevant allergens. Allergen immunotherapy is regularly recommended for treatment of allergic rhinitis due to pollen or dust mite allergy and for asthma if the symptoms are severe and if the patient wants to avoid medication and side effects.
High-impact journals are those considered to be highly influential in their respective fields.It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.
Last date updated on July, 2014