|Allergic rhinitis is defined as a symptomatic disorder of the nose, induced after allergen exposure due to an immunoglobulin (Ig) E-mediated inflammation of the membranes lining the nose. It is often linked to other atopic diseases such as food allergy, atopic dermatitis or asthma. Seasonal rhinitis is caused by aeroallergens like pollens while the persistent form is mostly induced by mites, mold, and dander. Although allergic rhinitis is not a life-threatening condition, it has important impact on the quality of life. Allergic rhinitis is characterized by a two phase allergic reaction: an initial sensitization phase where allergen exposure results in IgE formation as well as induction of the humoral response, and subsequent clinical disease after repeated antigen exposure. The symptoms of allergic rhinitis include rhinorrhea, sneezing, nasal itching and unilateral or bilateral nasal obstruction. Treatment of allergic rhinitis (AR) should be based Control of the environment, drug therapy and immunomodulating therapy.
The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.