Allergic rhinitis is defined as a symptomatic disorder of the nose, induced after allergen exposure due to an immunoglobulin (Ig) E-mediated inflammation of the membranes lining the nose. It is often linked to other atopic diseases such as food allergy, atopic dermatitis or asthma. Seasonal rhinitis is caused by aeroallergens like pollens while the persistent form is mostly induced by mites, mold, and dander. Although allergic rhinitis is not a life-threatening condition, it has important impact on the quality of life. Allergic rhinitis is characterized by a two phase allergic reaction: an initial sensitization phase where allergen exposure results in IgE formation as well as induction of the humoral response, and subsequent clinical disease after repeated antigen exposure. The symptoms of allergic rhinitis include rhinorrhea, sneezing, nasal itching and unilateral or bilateral nasal obstruction. Treatment of allergic rhinitis (AR) should be based Control of the environment, drug therapy and immunomodulating therapy. The most common agents to treat AR include antihistamines, decongestants, steroids, mast cell stabilizers, anticholinergic agents, antileukotrienes and mucolytics: topical corticosteroids are the preferred method of treatment for both seasonal and perennial allergic rhinitis.
Peer review refers to the work done during the screening of submitted manuscripts and funding applications. This process encourages authors to meet the accepted standards of their discipline and reduces the dissemination of irrelevant findings, unwarranted claims, unacceptable interpretations, and personal views. Publications that have not undergone peer review are likely to be regarded with suspicion by academic scholars and professionals.
Last date updated on July, 2014
