Patients with localized and well-differentiated disease are usually cured by hysterectomy and bilateral salpingo-ophorectomy alone. However, other patients may benefit from adjuvant therapy. It is important to keep in mind that adjuvant radiotherapy in patients with early-stage endometrial cancer has not been proven to increase overall survival. Its main role is that of preventing local recurrences which indirectly can have an important impact in the quality of life of these patients. There is much debate about the best adjuvant therapy after surgery and there are no accepted guidelines for this treatment. EC patients often receive adjuvant radiation therapy to reduce the risk of pelvic relapse but this does not seem to improve overall survival because it cannot reduce the risk of distant recurrences.
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Last date updated on July, 2014