Insulin resistance is defined as the resistance of tissues to the insulin action. In the periphery it is attributed to resistance to the uptake of glucose used by the muscles, liver, kidney and other organs, while in the brain it impairs insulin signaling. Insulin resistance involves the insulin receptors and is influenced by genetic predisposition as well as environmental factors such as feeding and obesity. Insulin resistance with hyperinsulinemia can precede the onset T2DM by several years. This pre-diabetic stage is responsible for vascular changes that may or may not be associated with other vascular risk factors (hypertension, dyslipidemia and obesity), which together comprise the metabolic syndrome.
Journal Article is sometimes called a Scientific Article, a Peer-Reviewed Article, or a Scholarly Research Article. Together, journal articles in a particular field are often referred to as The Literature.
Journal articles are most often Primary Research Articles. However, they can also be Review Articles. These types of articles have different aims and requirements. Sometimes, an article describes a new tool or method.
Because articles in scientific journals are specific, meticulously cited and peer-reviewed, journal databases are the best place to look for information on previous research on your species. Without a background in the field, journal articles may be hard to understand - however, you do not need to understand an entire article to be able to get valuable information from it.
Last date updated on October, 2014