clinical practice of Parkinson disease is a common in middle-aged and elderly chronic degenerative diseases of central nervous system is represented by L-dopa dopamine replacement therapy mainly, some researchers. In fact, 5-HTP is produced from tryptophan via the enzyme tryptophan hydroxylase. And then, 5-HTP is converted into serotonin via the enzyme L-amino acid decarboxylase. Then perfusion fixed, get in the brain, paraffin-embedded. In L-dopa dopamine replacement therapy are the main drug, its side effects are also very obvious that the latest studies suggest that L-dopa has resulted in the substantia nigra apoptosis.
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Last date updated on January, 2021