|clinical assessment scales, other assessment tools exist but are less frequently used. Skin surface topography using silicone impression-based grading is both a valid and reproducible measure of photo aging and dermal elastosis. Biopsies may be used to histological assess increases in collagen and elastin deposition or epidermal thickness but are invasive and leave scars. Newer measurement technologies include the corneometer which measures hydration of the epidermis, cutometer which measures skin elasticity, and digital programs such as VISIA which combine multispectral imaging and complexion analysis software to quantify certain characteristics of the skin topography and subsurface such as UV damage, brown spots, fine lines, texture, pore size, and redness. This review will focus on the evidence behind various novel and traditional anti aging therapies that have been popularized in recent years with emphasis on those those are strongly proven to be effective. Many novel and traditional anti aging therapies that have been popularized in recent years with emphasis on those those are strongly proven to be effective. Clinical scoring using validated assessment scales has proven to be highly reliable for the evaluation of the signs of facial aging including forehead lines, nasolabial folds, marionette lines, jawline, oral commissures, neck volume, glabellar lines, infraorbital hollow, upper cheek fullness, crowÃ¢â¬â¢s feet, lip fullness, and lip wrinkles. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.