Allergic contact dermatitis to mercaptobenzothiazole and its derivatives has been increasingly recognized in industrialized countries because of their widespread use in polymerization of synthetic rubber. Chemical additives are frequently used in polymerization of the rubber as vulcanization accelerators, whereby the list of products containing rubber mercaptobenzothiazole is so long. In addition to the rubber industry, they are used as fungicides and anti-corrosion products in the metal industry and mining industry to harvest gold and silver. The mercaptobenzothiazole and mercapto mix are well known allergens and their clinical importance as potential triggers of allergic contact dermatitis is decisive,
DCA to mercaptobenzothiazole can be observed in both children and adults but seems to be more frequent in males, probably due to the greater use of clothing with rubber additives.
Contact allergy to rubber in elastic textiles is well described .The low molecular weight group of mercaptobenzothiazole, consequent skin permeability and the existence of the thiol group capable of binding to amino acids and proteins are potential factors that favor sensitization. Facial Dermatitis to Mercaptobenzothiazole: Catarina AraÃºjo, Cristina Resende, Teresa Pereira and Celeste Brito
Last date updated on June, 2014