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Tissue Engineering New Findings

Tissue engineering/regenerative medicine promises to solve problems in organ transplantation crisis. Autogenous bone grafting is considered to be the gold standard for the treatment and management of bone defects like, craniofacial disorders and orthopedic conditions such as, fractures and non unions. 3D polymeric scaffolds can mimic the natural extracellular matrix of bone. Designing a scaffold with the required properties is a key factor that governs the bone tissue engineering. Complex porous 3D structures are fabricated by various processes like, foaming, salt leaching, emulsification etc. However, scaffolds fabricated by these conventional methods can only justify partial requirements of tissue engineering approaches. The major drawbacks of these procedures include lack of control in morphological characteristics like, pore shape, size, distribution and pore connectivity. One of the recent techniques that add complexity reminiscent of tissue engineering is Rapid Prototyping (RP) technology, which arranges/deposits drops or fibres of polymeric materials in required geometry. RP technology helps in designing 3D parts which are built layer-by-layer based on a Computer Aided Design (CAD) file. By far, there are number of commercial RP techniques available for different materials. Rapid Prototyping Technology in Bone Tissue Engineering: Md Enamul Hoque and R.G.S.V Prasad
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Last date updated on July, 2014

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