alexa Erectile Dysfunction|OMICS International| Andrology-Open Access

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Erectile Dysfunction

Erectile Dysfuntion (ED) is still a critical issue although the introduction of Phosphodiesterase-5 (PED-5) inhibitors in 1998 had shed much light into the field. Subsequently this agent has become the first-line drug in ED management. Vascular Dysfunction is believed to be a critical cause of male ED, which may be classified as venogenic, arteriogenic, or mixed. Among these, Veno-Occlusive Dysfunction (VOD) is the most prevalent in impotent patients and even in those caused by cigarette-smoking which was plausibly to be resulting from an arterial insufficiency. Thus, ED could be most often caused by diseased veins which have been known to be associated with various disease entities in the dependent portion of the upright human body such as hemorrhoids in the rectum, varicose veins in the leg, and varicocele testis. This belief was further underpinned after the study of the dramatic improvement in inducing a fully rigid erection when penile erection-related veins were being stripped and ligated at the tunical level in cadaveric penises. This finding of the pivotal role of penile veins may challenge the consensus of ED contributors which just enrolls hormonal deficiency, arterial insufficiency, neurotic disorders, and adverse effects from drugs, chronic systemic diseases, psychogenic origins and intracavmosal fibrosis. Should penile venous surgery be commensurately beneficial for ED patients if it works in both fresh and defrosted cadavers which are immune to be influenced by ED contributors above. (Geng-Long Hsu, A Physiological Approach to a Penile Venous Stripping Surgical Procedure for Patients with Erectile Dysfunction)
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Last date updated on November, 2020