|Sepsis is potentially fatal life threating complication of infection with whole body inflammation. Sepsis occurs when chemicals released into the blood to fight infection trigger inflammation. It can either be termed as septicemia. The majority of cases of sepsis are due to bacterial infections. Sepsis can either be treated by intravenous antibiotics, hospitalization and also by therapies to support any organ dysfunction. The non-medical term Blood poisoning refers to medical condition called sepsis. Treatment of sepsis, early diagnosis and Prevention of infections are the best ways to prevent sepsis or reduce the problems sepsis causes. Depending on the severity of sepsis the prognosis depends. High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.