alexa Thalassemia Open Access Articles|OMICS Group|Journal Of Blood Disorders And Transfusion

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Thalassemia Open Access Articles

Thalassemia is a disorder which is inherited from parents to children. Thalassemia is the most common type of hemoglubinopathies transmitted by hereditary. Thalassemia is classified into two major types, alpha and beta that are named after defects in these protein chains. The α thalassemias includes HBA1 and HBA2 genes. α Thalassemias involve in decreased alpha-globin production with fewer alpha-globin chains release continued with excess of β chains in adults and excess γ chains in new-borns. Beta thalassemia’s is because of mutations in the HBB gene on chromosome. The severity of thalassemia occurs with complications of including iron overload, bone deformities and cardiovascular illness. The disorder results in excessive destruction of red blood cells, which leads to anemia. Untreated, thalassemia major leads to heart failure and liver problems. Open access to the scientific literature means the removal of barriers (including price barriers) from accessing scholarly work. There are two parallel “roads” towards open access: Open Access articles and self-archiving. Open Access articles are immediately, freely available on their Web site, a model mostly funded by charges paid by the author (usually through a research grant). The alternative for a researcher is “self-archiving” (i.e., to publish in a traditional journal, where only subscribers have immediate access, but to make the article available on their personal and/or institutional Web sites (including so-called repositories or archives)), which is a practice allowed by many scholarly journals.
 
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