Thalassemia is a disorder which is inherited from parents to children. Thalassemia is the most common type of hemoglubinopathies transmitted by hereditary. Thalassemia is classified into two major types, alpha and beta that are named after defects in these protein chains. The Î± thalassemias includes HBA1 and HBA2 genes. Î± Thalassemias involve in decreased alpha-globin production with fewer alpha-globin chains release continued with excess of Î² chains in adults and excess Î³ chains in new-borns. Beta thalassemiaâs is because of mutations in the HBB gene on chromosome. The severity of thalassemia occurs with complications of including iron overload, bone deformities and cardiovascular illness. The disorder results in excessive destruction of red blood cells, which leads to anemia. Untreated, thalassemia major leads to heart failure and liver problems. Scientific journal is a periodical publication intended to further progress of science, usually by reporting novel research. There are thousands of scientific journals in publication, and many more have been published at various points in the past. Most journals are highly specialized, although some of the oldest journals publish articles and scientific papers across a wide range of scientific fields. Scientific journals contain articles that are peer reviewed, to ensure that articles meet the journal's standards of quality, and scientific validity.The publication of the results of research is an essential part of the scientific method. If they are describing experiments or calculations, they must supply enough details that an independent researcher could repeat the experiment or calculation to verify the results. Each such journal article becomes part of the permanent scientific record.
Last date updated on September, 2014