|Leukopenia is an abnormal diminishment of circulating white blood cells, especially the granulocytes. White blood cells are the soldiers of the human body that makeover the immune system. The term leukopenia is often used interchangeably with neutropenia. Neutropenia is mostly responsible because of medications, megaloblastosis, Infection, hypersplenism, genetic deficiencies and immunoneutropenia. Bur majority of the cases in neutropenia occurs due to infection. There will be greater risk to the individual which severely weakens the immune system. It may result from reduced production of white blood cells or increased utilization and destruction, or both. Management and prevention requires identification of the cause and effective antimicrobial therapy, especially when serious systemic infection is present. The treatment of this disease varies. Use of Antibiotics, Increase Essential Vitamin Intake, Prescribed Steroids, and Remove Causative Agents etc. are some remedies. Journal of Blood Disorders & transfusion journal is responsible for timely publication of the manuscripts and hope it would be useful for the Researchers, Research scholars, Academician, Industrialists, Consultancy for the development of science.