|Adrenocorticotropic hormone (ACTH) is a polypeptide hormone produced by the anterior pituitary gland. It is an essential element of the hypothalamic-pituitary-adrenal axis. Biological stress is responsible to stimulate the release of ACTH from pituitary gland. It plays a key role in the production and release of corticosteroids from adrenal gland.A journalÂ is aÂ periodical publicationÂ intended to further progress ofÂ science, usually by reporting newÂ research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, andÂ scientific papersÂ across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientificÂ validity. Each such journal article becomes part of the permanent scientific record.