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Hui-Wen Lo | OMICS International
ISSN: 2157-2518

Journal of Carcinogenesis & Mutagenesis
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Hui-Wen Lo


Regulation of Apoptosis by HER2 in Breast Cancer

HER2 is a trans-membrane receptor tyrosine kinase that activates multiple growth-promoting signaling pathways including PI3K-AKT and Ras-MAPK. Dysregulation of HER2 is a frequent occurrence in breast cancer that is associated with poor patient outcomes. A primary function of HER2 is suppressing apoptosis to enhance cell survival giving rise to unco... Read More»

Richard L Carpenter and Hui-Wen Lo

Review Article: J Carcinog Mutagen 2013, S7- 003

DOI: 10.4172/2157-2518.S7-003

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article