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Patricia Rafferty | OMICS International
ISSN: 2157-2518

Journal of Carcinogenesis & Mutagenesis
Open Access

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Patricia Rafferty

USA
Publications

Tissue Factor (TF) Expression and Angiogenesis in Tumor Progression and Inhibition of Tumor Growth by Anti-TF Antibodies in Human Tissue Factor Knock-In Mice

Background: Tissue factor (TF) serves as the primary initiator of the extrinsic pathway of blood coagulation and mediates signaling via the protease activated receptor-2 (PAR2). TF is over-expressed in several tumor types and may facilitate tumor progression and angiogenesis. To test the hypothesis that inhibition of TF may have an anti-tumor effec... Read More»

Amy L. Volk, Laura Johns, Heena Beck, Francis L. McCabe, Patricia Rafferty, Devon D. Egenolf, Hillary Millar, Jin Lu, Barry Morse, Mark Anderson and Peter J. Bugelski

Research Article: J Carcinog Mutagen 2013,S7- 001

DOI: 10.4172/2157-2518.S7-001

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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